If you have an allergy to diclofenac or any other part of diclofenac gel (1%). Using this medicine with any of the following medicines is not recommended. WebDiclofenac sodium overdose. It may be hard to tell unless your doctor monitors your kidney function. Check with your doctor right away if you notice any of these warning signs. information and will only use or disclose that information as set forth in our notice of Do not use it more often than directed. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Common side effects of diclofenac topical may include: heartburn, gas, stomach pain, nausea, vomiting; skin redness, itching, dryness, scaling, or peeling where the medicine was applied. You should not use this medicine if you are allergic to diclofenac (Voltaren, Cataflam, Flector, and others), or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Safety and efficacy have not been established. COMMON BRAND NAME(S): DICLOVIX, INFLAMMA-K, PENNSAID, PROFINAC, VOPAC MDS, Xrylix II. Kidney problems can sometimes occur with the use of NSAID medications, including diclofenac. Several weeks may pass before you feel the full effects of this medicine. Smoking, drinking alcohol, older age, and poor health can also increase risks. Can ibuprofen gel affect your kidneys? This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Tell your diclofenac topical is for use on the hands, wrists, elbows, knees, ankles, or feet. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Do not stand up or sit up quickly, especially if you are an older patient. It works by decreasing inflammation. Older adults may be at greater risk for stomach/intestinal bleeding, kidney problems, heart attack, and stroke while using this drug. If you notice any other effects, check with your healthcare professional. information and will only use or disclose that information as set forth in our notice of Talk with your doctor. Be sure to read this information carefully each time. This medicine comes with a dosing card. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. These side effects may go away during treatment as your body adjusts to the medicine. If you are allergic to diclofenac gel (1%); any part of diclofenac gel (1%); or any other drugs, foods, or substances. It will not prevent or lessen the number of migraine attacks. The presence of other medical problems may affect the use of this medicine. include protected health information. This medicine may cause a delay in ovulation for women and may affect their ability to have children. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. If it is near the time of the next dose, skip the missed dose. Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), liver disease, stomach/intestine problems (such as bleeding, ulcers), heart disease (such as previous heart attack), high blood pressure, stroke, swelling (edema, fluid retention), diabetes, blood disorders (such as anemia), bleeding/clotting problems, growths in the nose (nasal polyps). Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. AdultsOne packet (50 milligrams) as a single, one time dose. Do not use heat or bandages on the treated part. It is very important that your doctor check your progress at regular visits. Topical non-steroidal anti-inflammatories, Detailed Diclofenac topical dosage information, Drug class: topical non-steroidal anti-inflammatories. Review/update the Diclofenac Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is a nonsteroidal anti-inflammatory drug (NSAID). If putting diclofenac gel (1%) on the hand, do not wash your hands for at least 1 hour after putting on. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Call your doctor or get medical To provide you with the most relevant and helpful information, and understand which The official prescribing information for diclofenac Diclofenac topical can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not freeze. This medicine should come with a Medication Guide. If you do, rinse your eyes with plenty of cool tap water. Be careful brushing or flossing your teeth or using a toothpick because you may get an infection or bleed more easily. Shortness of breath, a big weight gain, or swelling in the arms or legs. Do not increase your dose or use this drug more often or for longer than prescribed. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Talk to your pharmacist for more details. decrease in urine output or decrease in urine-concentrating ability, stomach bloating, burning, cramping, discomfort, upset, or pain, sores, ulcers, or white spots on the lips or in the mouth, vomiting of blood or material that looks like coffee grounds, Blistering, peeling, loosening of the skin, burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, feeling of constant movement of self or surroundings, pain or discomfort in the arms, jaw, back, or neck, red skin lesions, often with a purple center, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, change in the ability to see colors, especially blue or yellow, irregular, fast or slow, or shallow breathing, pain or discomfort in the chest, upper stomach, or throat, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, unusual drowsiness, dullness, or feeling of sluggishness, continuing ringing or buzzing or other unexplained noise in the ears, excess air or gas in the stomach or intestines, increased sensitivity of the skin to sunlight, redness, pain, swelling of the eye, eyelid, or inner lining of eyelid, redness or other discoloration of the skin. However, do not use this medicine more often or for a longer time than your doctor ordered. Put on a missed dose as soon as you think about it. Portions of this document last updated: May 01, 2023. Drug interactions may change how your medications work or increase your risk for serious side effects. Advertising revenue supports our not-for-profit mission. information highlighted below and resubmit the form. Keep taking it unless your care team tells you to stop. taken, how much, and when it happened. gel 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). health information, we will treat all of that information as protected health The renal plasma flow and the glomerular filtration rate initially diminished significantly, by 35%, but began to increase after only 2 hours. Diclofenac sodium overdose For oral dosage form (Zorvolex capsules): Adults18 or 35 milligrams (mg) 3 times a day. Read and carefully follow any Instructions for Use provided with your medicine. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Do not take diclofenac gel (1%) if you are in the third trimester of pregnancy. Your care team will monitor you closely if you need to take it. include protected health information. Taking this medication between weeks 20 and 30 of pregnancy may harm your unborn baby. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Follow all instructions closely. Dosage forms: topical cream (1%), topical gel (1%; 3%), topical kit (1%), topical solution (1.5%; 2%) Allergy to bovine proteinZipsor capsule contains gelatin and should not be used in patients with this condition. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Signs of high blood pressure like very bad. Advertising revenue supports our not-for-profit mission. The official prescribing information for diclofenac warns that long-term administration could cause renal injury. It is not clear whether you would absorb enough diclofenac from a topical gel to harm your kidneys. This is best determined by frequent monitoring. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Tell your doctor about the allergy and We comply with the HONcode standard for trustworthy health information. Avoid tanning booths and sunlamps. If your symptoms or health problems do not get better or if they become worse, call your doctor. May make these conditions worse. NOTE: This medicine is only for you. Also call your doctor at once if you have: severe headache, blurred vision, pounding in your neck or ears; liver problems--nausea, diarrhea, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or. I suffered kidney damage from extended use of ibuprofen. Diclofenac is known as a nonsteroidal anti-inflammatory drug (NSAID). May make these conditions worse. Am I absorbing enough of this product to be harmful? Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Copyright 1996-2023 Cerner Multum, Inc. 2. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine. Using this medicine during the later part of pregnancy can harm your unborn baby. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. WebDehydration; history of asthma; history of confirmed or suspected cerebrovascular bleeding; history of haemorrhagic diathesis; hypovolaemia; operations with high risk of haemorrhage With systemic use Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Avoid getting diclofenac topical in your eyes. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. All rights reserved. This medicine is not for long-term use. This is a decision you and your doctor will make. Ask your doctor if you should use sunscreen along with this medication. Kidney disease, severeShould not be used in patients with these conditions. Topical non-steroidal anti-inflammatories, Detailed Diclofenac topical dosage information, Drug class: topical non-steroidal anti-inflammatories. Avoid exposing treated skin to heat, sunlight, or tanning beds. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Advertising on our site helps support our mission. Take the medication to a medication take-back program. taking drugs like this one after a first heart attack were also more likely to die in the year after the heart attack compared with people not Limit your time in the sun. If you are looking for a nondrug approach to easing the pain of arthritis or a muscle strain, you will find some helpful ideas in our online Guide to Alternatives for Arthritis. My nephrologist and urologist said nothing could be done. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor). Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. It may take up to 30 days after finishing the medication for the skin to completely heal. Keep out of the reach of children and pets. Mayo Clinic does not endorse companies or products. Avoid drinking alcohol. Diclofenac sodium gel, 3% should not be applied to open skin wounds, infections, or exfoliative dermatitis. Ask your doctor about any risk. the unsubscribe link in the e-mail. If you do get the medication in those areas, flush with plenty of water. Keep out of your mouth, nose, and eyes (may burn). Do not use extra or 2 doses at the same time to make up for the missed dose. Your doctor may direct you to take 100 mg for the first dose only. Keep all medical and lab appointments. Diclofenac topical may also cause stomach or intestinal bleeding, which can be fatal. However, elderly patients are more likely to have age-related kidney or stomach problems, which may require caution for patients receiving diclofenac. These drugs are similar to diclofenac and may increase your risk of side effects if taken together. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Make sure you tell your doctor if you have any other medical problems, especially: Keep using this medicine for the full time of treatment. OTC NSAIDs generally are considered safe when they are used as directed, but extensive data showing evidence of renal dysfunction (changes in serum urea or creatinine Diclofenac sodium topical gel is a medication that treats arthritis of the knee. Put a thin layer on the affected skin and rub in gently.